Status of group B streptococcal vaccine development

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Status of group B streptococcal vaccine development

Streptococcus agalactiae (group B streptococcus, GBS) is a leading causal organism of neonatal invasive diseases and severe infections in the elderly. Despite significant advances in the diagnosis and treatment of GBS infections and improvement in personal hygiene standards, this pathogen is still a global health concern. Thus, an effective vaccine against GBS would augment existing strategies ...

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Group B streptococcal epidemiology and vaccine needs in developed countries.

Development of a group B streptococcal vaccine (GBS) vaccine is the most promising approach for the prevention of GBS infections in babies, given the potential adverse effects of intrapartum antibiotic prophylaxis as well as the need for effective prevention of both adult and late perinatal disease. There are numerous prevention strategies at this time but none are 100% effective in the eradica...

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Group B Streptococcal Sepsis in a Newborn: a Case Report

Newborns’ bacterial infections due to group B Streptococcus (GBS) happen in two forms including early-onset disease or late-onset disease. In this paper, we report a case of early-onset GBS infection in a male infant. A 22-year-old primigravid woman delivers a term normal looking male infant. Nasal flaring, grunting, and poor feeding presented soon after birth. An empiric treatment wit...

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Group B Streptococcal Infections.

Group B streptococcal disease remains a prominent cause of infectious morbidity in pregnant women and their infants. This article highlights recent developments that are relevant for obstetricians, perinatologists, and neonatologists caring for patients with group B streptococcal disease. The morbidity of group B streptococcal infections in pregnancy and the proposed association of colonization...

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Group B Streptococcal Myocarditis

Bacterial myocarditis is an uncommon form of infectious myocarditis. The definitive diagnosis requires histopathology with evidence of bacterial invasion. We report a case of group B streptococcal myocarditis secondary to septicaemia with complete atrioventricular (AV) block and new left bundle branch block. The histopathology revealed patchy small foci of myocyte necrosis. The necrotic areas c...

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ژورنال

عنوان ژورنال: Clinical and Experimental Vaccine Research

سال: 2018

ISSN: 2287-3651,2287-366X

DOI: 10.7774/cevr.2018.7.1.76